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Cancer cells activate p53 in response to 10-formyltetrahydrofolate dehydrogenase expression
A folate enzyme, FDH (10-formyltetrahydrofolate dehydrogenase; EC 1.5.1.6), is not a typical tumour suppressor, but it has two basic characteristics of one, i.e. it is down-regulated in tumours and its expression is selectively cytotoxic to cancer cells. We have recently shown that ectopic expressio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1276951/ https://ncbi.nlm.nih.gov/pubmed/16014005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050533 |
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