Rapamycin Protects Spiral Ganglion Neurons from Gentamicin-Induced Degeneration In Vitro

Gentamicin, one of the most widely used aminoglycoside antibiotics, is known to have toxic effects on the inner ear. Taken up by cochlear hair cells and spiral ganglion neurons (SGNs), gentamicin induces the accumulation of reactive oxygen species (ROS) and initiates apoptosis or programmed cell dea...

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Detaylı Bibliyografya
Yayımlandı:J Assoc Res Otolaryngol
Asıl Yazarlar: Guo, Shasha, Xu, Nana, Chen, Peng, Liu, Ying, Qi, Xiaofei, Liu, Sheng, Li, Cuixian, Tang, Jie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797692/
https://ncbi.nlm.nih.gov/pubmed/31236744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-019-00717-3
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