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Rapamycin Protects Spiral Ganglion Neurons from Gentamicin-Induced Degeneration In Vitro

Gentamicin, one of the most widely used aminoglycoside antibiotics, is known to have toxic effects on the inner ear. Taken up by cochlear hair cells and spiral ganglion neurons (SGNs), gentamicin induces the accumulation of reactive oxygen species (ROS) and initiates apoptosis or programmed cell dea...

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Foilsithe in:J Assoc Res Otolaryngol
Main Authors: Guo, Shasha, Xu, Nana, Chen, Peng, Liu, Ying, Qi, Xiaofei, Liu, Sheng, Li, Cuixian, Tang, Jie
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer US 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797692/
https://ncbi.nlm.nih.gov/pubmed/31236744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-019-00717-3
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