Spleen tyrosine kinase activity regulates epidermal growth factor receptor signaling pathway in ovarian cancer

BACKGROUND: Spleen tyrosine kinase (SYK) is frequently upregulated in recurrent ovarian carcinomas, for which effective therapy is urgently needed. SYK phosphorylates several substrates, but their translational implications remain unclear. Here, we show that SYK interacts with EGFR and ERBB2, and di...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Yu, Yu, Suryo Rahmanto, Yohan, Shen, Yao-An, Ardighieri, Laura, Davidson, Ben, Gaillard, Stephanie, Ayhan, Ayse, Shi, Xu, Xuan, Jianhua, Wang, Tian-Li, Shih, Ie-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796592/
https://ncbi.nlm.nih.gov/pubmed/31492560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.055
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados