B7-H3-redirected chimeric antigen receptor T cells target glioblastoma and neurospheres

BACKGROUND: The dismal survival of glioblastoma (GBM) patients urgently calls for the development of new treatments. Chimeric antigen receptor T (CAR-T) cells are an attractive strategy, but preclinical and clinical studies in GBM have shown that heterogeneous expression of the antigens targeted so...

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Bibliografische gegevens
Gepubliceerd in:EBioMedicine
Hoofdauteurs: Nehama, Dean, Di Ianni, Natalia, Musio, Silvia, Du, Hongwei, Patané, Monica, Pollo, Bianca, Finocchiaro, Gaetano, Park, James J.H., Dunn, Denise E., Edwards, Drake S., Damrauer, Jeffrey S., Hudson, Hannah, Floyd, Scott R., Ferrone, Soldano, Savoldo, Barbara, Pellegatta, Serena, Dotti, Gianpietro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
Onderwerpen:
Research paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796553/
https://ncbi.nlm.nih.gov/pubmed/31466914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.030
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