Utilizing the genomically adjusted radiation dose (GARD) to personalize adjuvant radiotherapy in triple negative breast cancer management

BACKGROUND: Utilizing the linear quadratic model and the radiosensitivity index (RSI), we have derived an expression for the genomically adjusted radiation dose (GARD) to model radiation dose effect. We hypothesize GARD is associated with local recurrence and can be used to optimize individual tripl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EBioMedicine
Main Authors: Ahmed, Kamran A., Liveringhouse, Casey L., Mills, Matthew N., Figura, Nicholas B., Grass, G. Daniel, Washington, Iman R., Harris, Eleanor E., Czerniecki, Brian J., Blumencranz, Peter W., Eschrich, Steven A., Scott, Jacob G., Diaz, Roberto, Torres-Roca, Javier F.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Research paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796536/
https://ncbi.nlm.nih.gov/pubmed/31416721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.019
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