Utilizing the genomically adjusted radiation dose (GARD) to personalize adjuvant radiotherapy in triple negative breast cancer management

BACKGROUND: Utilizing the linear quadratic model and the radiosensitivity index (RSI), we have derived an expression for the genomically adjusted radiation dose (GARD) to model radiation dose effect. We hypothesize GARD is associated with local recurrence and can be used to optimize individual tripl...

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Библиографические подробности
Опубликовано в: :EBioMedicine
Главные авторы: Ahmed, Kamran A., Liveringhouse, Casey L., Mills, Matthew N., Figura, Nicholas B., Grass, G. Daniel, Washington, Iman R., Harris, Eleanor E., Czerniecki, Brian J., Blumencranz, Peter W., Eschrich, Steven A., Scott, Jacob G., Diaz, Roberto, Torres-Roca, Javier F.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2019
Предметы:
Research paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796536/
https://ncbi.nlm.nih.gov/pubmed/31416721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.019
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