Utilizing the genomically adjusted radiation dose (GARD) to personalize adjuvant radiotherapy in triple negative breast cancer management

BACKGROUND: Utilizing the linear quadratic model and the radiosensitivity index (RSI), we have derived an expression for the genomically adjusted radiation dose (GARD) to model radiation dose effect. We hypothesize GARD is associated with local recurrence and can be used to optimize individual tripl...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Ahmed, Kamran A., Liveringhouse, Casey L., Mills, Matthew N., Figura, Nicholas B., Grass, G. Daniel, Washington, Iman R., Harris, Eleanor E., Czerniecki, Brian J., Blumencranz, Peter W., Eschrich, Steven A., Scott, Jacob G., Diaz, Roberto, Torres-Roca, Javier F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796536/
https://ncbi.nlm.nih.gov/pubmed/31416721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.019
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