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P11.54 Identification of PDGFRA and MYC(N) as somatic driver genes in Glioblastoma

BACKGROUND: Somatic oncogene amplification happens frequently in glioblastoma (GBM). The second most frequently amplified gene encoding receptor tyrosine kinases in GBMs is platelet derived growth factor alpha (PDGFRA) (15%). In contrast, MYC and MYCN amplification occurs in 1.6% and 2.9%, respectiv...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Berezovsky, A D, Transou, A, Irtenkauf, S, Poisson, L, Hank Wu, K, Mikkelsen, T, deCarvalho, A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796107/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.200
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