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P05.04 Phase 2 open-label study of maintenance treatment with ibrutinib following first line methotrexate-based immuno-chemotherapy in elderly patients with primary CNS lymphoma (PCNSL)

BACKGROUND: Patients older than 60 years account for up to 70% of all PCNSL cases. Elderly PCNSL patients have median overall survival (OS) under 2 years and progression free survival (PFS) ranging between 6–16 months. Older patients have multiple comorbidities associated with low tolerability to hi...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Bairey, O, Amiel, A, Yust-Katz, S, Gurion, R, Siegal, T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796039/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.118
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