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P15.05 High-dose methotrexate based immuno-chemotherapy with maintenance chemotherapy with High-dose methotrexate and deferred radiotherapy for elderly primary CNS lymphoma patients

Introduction: High-dose methotrexate (HD-MTX)-based chemotherapy with whole brain irradiation (WBRT) improves the prognosis of PCNSL. However, the high neurotoxicity rates observed, especially in the elderly, raised interest in chemotherapy-only treatments. Withholding radiotherapy substantially dec...

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Mishima, K., Miyake, Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463948/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.415
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