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ACTR-23. MAINTENANCE TREATMENT WITH IBRUTINIB FOLLOWING FIRST LINE METHOTREXATE-BASED IMMUNO-CHEMOTHERAPY IN ELDERLY PATIENTS WITH PRIMARY CNS LYMPHOMA (PCNSL). A PHASE 2 OPEN-LABEL STUDY

BACKGROUND: Patients older than 60 years account for up to 70% of all PCNSL cases. Elderly PCNSL patients have median overall survival (OS) under 2 years and progression free survival (PFS) ranging between 6–16 months. Older patients have multiple comorbidities associated with low tolerability to hi...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Bairey, Osnat, Benouaich-amiel, Alexandra, Yust-Katz, Shlomit, Gurion, Ronit, Siegal, Tali
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847396/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.066
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