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P04.15 Impact of histone lysine methyltransferases SETDB1, SETD2, SUV39H1, MLL2, EZH2and their corresponding histone marks in pediatric astrocytomas

BACKGROUND: Pediatric brain tumors are characterized by altered epigenetic profiles and deregulated chromatin remodelling that affects gene expression. Histone lysine methylation has emerged as important chromatin function regulator, with potential role in glioma formation. Τhis study investigates t...

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發表在:Neuro Oncol
Main Authors: Klonou, A, Korkolopoulou, P, Gargalionis, A N, Themistocleous, M, Sgouros, S, Papavassiliou, A G, Piperi, C
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795778/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.110
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