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P04.15 Impact of histone lysine methyltransferases SETDB1, SETD2, SUV39H1, MLL2, EZH2and their corresponding histone marks in pediatric astrocytomas

BACKGROUND: Pediatric brain tumors are characterized by altered epigenetic profiles and deregulated chromatin remodelling that affects gene expression. Histone lysine methylation has emerged as important chromatin function regulator, with potential role in glioma formation. Τhis study investigates t...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Klonou, A, Korkolopoulou, P, Gargalionis, A N, Themistocleous, M, Sgouros, S, Papavassiliou, A G, Piperi, C
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795778/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.110
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