Neuronal Cell-Intrinsic Defects in Mouse Models of Down Syndrome

Down Syndrome (DS) is the most common genetic disorder associated with intellectual disability (ID). Excitatory neurons of DS patients and mouse models show decreased size of dendritic field and reduction of spine density. Whether these defects are caused by cell autonomous alterations or by abnorma...

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Publicado en:Front Neurosci
Autores principales: Chiotto, Alessandra Maria Adelaide, Migliorero, Martina, Pallavicini, Gianmarco, Bianchi, Federico Tommaso, Gai, Marta, Di Cunto, Ferdinando, Berto, Gaia Elena
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795679/
https://ncbi.nlm.nih.gov/pubmed/31649502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.01081
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