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CENPE Inhibition Leads to Mitotic Catastrophe and DNA Damage in Medulloblastoma Cells

SIMPLE SUMMARY: Medulloblastoma (MB) is the most frequent brain tumor in children. The standard treatment consists in surgery, followed by radiotherapy and chemotherapy. These therapies are only partially effective, since many patients still die and those who survive suffer from neurological and end...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Iegiani, Giorgia, Gai, Marta, Di Cunto, Ferdinando, Pallavicini, Gianmarco
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957796/
https://ncbi.nlm.nih.gov/pubmed/33804489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051028
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