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Neuronal Cell-Intrinsic Defects in Mouse Models of Down Syndrome

Down Syndrome (DS) is the most common genetic disorder associated with intellectual disability (ID). Excitatory neurons of DS patients and mouse models show decreased size of dendritic field and reduction of spine density. Whether these defects are caused by cell autonomous alterations or by abnorma...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Chiotto, Alessandra Maria Adelaide, Migliorero, Martina, Pallavicini, Gianmarco, Bianchi, Federico Tommaso, Gai, Marta, Di Cunto, Ferdinando, Berto, Gaia Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795679/
https://ncbi.nlm.nih.gov/pubmed/31649502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.01081
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