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The effects of manipulating levels of replication initiation factors on origin firing efficiency in yeast
Chromosome replication in Saccharomyces cerevisiae is initiated from ~300 origins that are regulated by DNA sequence and by the limited abundance of six trans-acting initiation proteins (Sld2, Sld3, Dpb11, Dbf4, Sld7 and Cdc45). We set out to determine how the levels of individual factors contribute...
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| Publicado en: | PLoS Genet |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6795477/ https://ncbi.nlm.nih.gov/pubmed/31584938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008430 |
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