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Genomic mapping of single-stranded DNA in hydroxyurea-challenged yeasts identifies origins of replication
We report a genome-wide analysis of single-stranded DNA formation during DNA replication in wild type and checkpoint-deficient rad53 yeast cells in the presence of hydroxyurea. In wild type cells, ssDNA first appears at a subset of replication origins and later “migrates” bi-directionally, suggestin...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2006
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1414058/ https://ncbi.nlm.nih.gov/pubmed/16429127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1358 |
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