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Replication in Hydroxyurea: It's a Matter of Time
Hydroxyurea (HU) is a DNA replication inhibitor that negatively affects both the elongation and initiation phases of replication and triggers the “intra-S phase checkpoint.” Previous work with budding yeast has shown that, during a short exposure to HU, MEC1/RAD53 prevent initiation at some late S p...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2099622/ https://ncbi.nlm.nih.gov/pubmed/17636020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00719-07 |
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