Characterization of ANGPTL4 function in macrophages and adipocytes using Angptl4-knockout and Angptl4-hypomorphic mice

Angiopoietin-like protein (ANGPTL)4 regulates plasma lipids, making it an attractive target for correcting dyslipidemia. However, ANGPTL4 inactivation in mice fed a high fat diet causes chylous ascites, an acute-phase response, and mesenteric lymphadenopathy. Here, we studied the role of ANGPTL4 in...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Oteng, Antwi-Boasiako, Ruppert, Philip M. M., Boutens, Lily, Dijk, Wieneke, van Dierendonck, Xanthe A. M. H., Olivecrona, Gunilla, Stienstra, Rinke, Kersten, Sander
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795085/
https://ncbi.nlm.nih.gov/pubmed/31409739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M094128
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