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OS6.1 Targeting Purine Metabolism to Overcome Therapeutic Resistance in Glioblastoma

BACKGROUND: A distinguishing characteristic of all cancers is uncontrolled cell division, and they require additional nucleotide bases such as purines, the building blocks of DNA and RNA, to sustain their uncontrolled growth. Purines can be synthesized from scratch by de novo pathway or salvaged by...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Ahmed, A U, Shireman, J, Atashi, F, Saathoff, M, Ali, E, Lee, G, Park, C, Savchuk, S, Rayyan, J, James, C, Ben-Sahra, I
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795030/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.039
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