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Association of TREM-1, IL-1β, IL-33/ST2, and TLR Expressions With the Pathogenesis of Ocular Toxoplasmosis in Mouse Models on Different Genetic Backgrounds

Ocular toxoplasmosis (OT) is one of the most common causes of posterior uveitis. The signaling of triggering receptor expressed on myeloid cells (TREM)-1 amplifies inflammation, whereas TREM-2 signaling is anti-inflammatory. IL-1β is a major driver of inflammation during infection. Toll-like recepto...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Zhang, Yanxia, He, Jian, Zheng, Huanqin, Huang, Shiguang, Lu, Fangli
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794992/
https://ncbi.nlm.nih.gov/pubmed/31649630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02264
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