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Association of TREM-1, IL-1β, IL-33/ST2, and TLR Expressions With the Pathogenesis of Ocular Toxoplasmosis in Mouse Models on Different Genetic Backgrounds

Ocular toxoplasmosis (OT) is one of the most common causes of posterior uveitis. The signaling of triggering receptor expressed on myeloid cells (TREM)-1 amplifies inflammation, whereas TREM-2 signaling is anti-inflammatory. IL-1β is a major driver of inflammation during infection. Toll-like recepto...

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Detalhes bibliográficos
Main Authors: Yanxia Zhang, Jian He, Huanqin Zheng, Shiguang Huang, Fangli Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-10-01
Colecção:Frontiers in Microbiology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fmicb.2019.02264/full
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