Co-mutations of TP53 and KRAS serve as potential biomarkers for immune checkpoint blockade in squamous-cell non-small cell lung cancer: a case report

BACKGROUND: Unprecedented durable responses are identified in clinical studies to target the signaling of programmed cell death protein-1 (PD-1) as well as its ligand (PD-L1) in patients with squamous-cell non-small cell lung cancer (NSCLC). However, factors predicting the patient subtypes that are...

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Bibliographic Details
Published in:BMC Med Genomics
Main Authors: Fang, Cheng, Zhang, Chu, Zhao, Wei-Qing, Hu, Wen-Wei, Wu, Jun, Ji, Mei
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794845/
https://ncbi.nlm.nih.gov/pubmed/31619231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0592-6
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