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Late Compartments of Amyloid Precursor Protein Transport in SY5Y Cells Are Involved in β-Amyloid Secretion

Amyloid plaques, composed mainly of the 39–43 amino acid βA4 peptide, are a characteristic feature of Alzheimer’s disease. Generation of βA4 by proteolytic processing of the amyloid precursor protein (APP) is thought to occur in a pathway that includes the activity of two as yet unknown proteases, w...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Peraus, Gisela C., Masters, Colin L., Beyreuther, Konrad
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793894/
https://ncbi.nlm.nih.gov/pubmed/9315893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-20-07714.1997
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