Mice Lacking Ataxin-1 Display Learning Deficits and Decreased Hippocampal Paired-Pulse Facilitation

Spinocerebellar ataxia type 1 (SCA1) is a neurodegenerative disorder characterized by ataxia, progressive motor deterioration, and loss of cerebellar Purkinje cells. To investigate SCA1 pathogenesis and to gain insight into the function of the SCA1 gene product ataxin-1, a novel protein without homo...

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Publicado en:J Neurosci
Autores principales: Matilla, Antoni, Roberson, Erik D., Banfi, Sandro, Morales, Joanella, Armstrong, Dawna L., Burright, Eric N., Orr, Harry T., Sweatt, John D., Zoghbi, Huda Y., Matzuk, Martin M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1998
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793485/
https://ncbi.nlm.nih.gov/pubmed/9651231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-14-05508.1998
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