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The Nuclear Export Inhibitor Selinexor Inhibits Hypoxia Signaling Pathways And 3D Spheroid Growth Of Cancer Cells

PURPOSE: The nucleocytoplasmic transport of macromolecules is critical for both cell physiology and pathophysiology. Exportin 1 (XPO1), the major nuclear export receptor, is involved in the cellular adaptation to reduced oxygen availability by controlling the nuclear activity of the hypoxia-inducibl...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Onco Targets Ther
Päätekijät: Depping, Reinhard, von Fallois, Moritz, Landesman, Yosef, Kosyna, Friederike Katharina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793465/
https://ncbi.nlm.nih.gov/pubmed/31632086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S213208
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