Isoform-Specific Effect of Apolipoprotein E on Cell Survival and β-Amyloid-Induced Toxicity in Rat Hippocampal Pyramidal Neuronal Cultures

Although the genetic link between the ε4 allele of apolipoprotein E (apoE) and Alzheimer’s disease is well established, the isoform-specific activity of apoE underlying this correlation remains unclear. To determine whether apoE influences the neurotoxic actions of β-amyloid (Aβ), we examined the ef...

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Publicat a:J Neurosci
Autors principals: Jordán, Joaquín, Galindo, María F., Miller, Richard J., Reardon, Catherine A., Getz, Godfrey S., LaDu, Mary Jo
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1998
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793392/
https://ncbi.nlm.nih.gov/pubmed/9412500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-01-00195.1998
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