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Apolipoprotein E structural requirements for the formation of SDS-stable complexes with beta-amyloid-(1-40): the role of salt bridges.

Of the three major isoforms of human apolipoprotein E (apoE), apoE4 is a risk factor for the development of Alzheimer's disease. Among possible neurologically relevant differences in the properties of apoE3 and apoE4 is the fact that apoE3 forms an SDS-stable complex with beta-amyloid-(1-40) (A...

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書誌詳細
主要な著者: Bentley, Nicholas M, Ladu, Mary Jo, Rajan, Chandrika, Getz, Godfrey S, Reardon, Catherine A
フォーマット: Artigo
言語:Inglês
出版事項: 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222763/
https://ncbi.nlm.nih.gov/pubmed/12015813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020207
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