Activity of the δ-Opioid Receptor Is Partially Reduced, Whereas Activity of the κ-Receptor Is Maintained in Mice Lacking the μ-Receptor

Previous pharmacological studies have indicated the possible existence of functional interactions between μ-, δ- and κ-opioid receptors in the CNS. We have investigated this issue using a genetic approach. Here we describe in vitro and in vivo functional activity of δ- and κ-opioid receptors in mice...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Matthes, H. W. D., Smadja, C., Valverde, O., Vonesch, J.-L., Foutz, A. S., Boudinot, E., Denavit-Saubié, M., Severini, C., Negri, L., Roques, B. P., Maldonado, R., Kieffer, B. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793240/
https://ncbi.nlm.nih.gov/pubmed/9736649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-18-07285.1998
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