Survival of Cultured Neurons from Amyloid Precursor Protein Knock-Out Mice against Alzheimer’s Amyloid-β Toxicity and Oxidative Stress

Studies on the amyloid precursor protein (APP) have suggested that it may be neuroprotective against amyloid-β (Aβ) toxicity and oxidative stress. However, these findings have been obtained from either transfection of cell lines and mice that overexpress human APP isoforms or pretreatment of APP-exp...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: White, Anthony R., Zheng, Hui, Galatis, Denise, Maher, Fran, Hesse, Lars, Multhaup, Gerd, Beyreuther, Konrad, Masters, Colin L., Cappai, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793217/
https://ncbi.nlm.nih.gov/pubmed/9698314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-16-06207.1998
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