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Cyclin-Dependent Kinase 5-Deficient Mice Demonstrate Novel Developmental Arrest in Cerebral Cortex

The cerebral cortex of mice with a targeted disruption in the gene for cyclin-dependent kinase 5 (cdk5) is abnormal in its structure. Bromodeoxyuridine labeling reveals that the normal inside-out neurogenic gradient is inverted in the mutants; earlier born neurons are most often found superficial to...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Gilmore, Edward C., Ohshima, Toshio, Goffinet, André M., Kulkarni, Ashok B., Herrup, Karl
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793186/
https://ncbi.nlm.nih.gov/pubmed/9698328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-16-06370.1998
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