Nitric Oxide-Dependent Production of cGMP Supports the Survival of Rat Embryonic Motor Neurons Cultured with Brain-Derived Neurotrophic Factor

Trophic factor deprivation induces neuronal nitric oxide synthase (NOS) and apoptosis of rat embryonic motor neurons in culture. We report here that motor neurons constitutively express endothelial NOS that helps support the survival of motor neurons cultured with brain-derived neurotrophic factor (...

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Pubblicato in:J Neurosci
Autori principali: Estévez, Alvaro G., Spear, Nathan, Thompson, J. Anthony, Cornwell, Trudy L., Radi, Rafael, Barbeito, Luis, Beckman, Joseph S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1998
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793136/
https://ncbi.nlm.nih.gov/pubmed/9570801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-10-03708.1998
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