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Nitric Oxide Depresses GABA(A) Receptor Function via Coactivation of cGMP-Dependent Kinase and Phosphodiesterase

Nitric oxide (NO) is thought to play an essential role in neuronal processing, but the downstream mechanisms of its action remain unclear. We report here that NO analogs reduce GABA-gated currents in cultured retinal amacrine cells via two distinct, but convergent, cGMP-dependent pathways. Either ex...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Wexler, Eric M., Stanton, Patric K., Nawy, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793112/
https://ncbi.nlm.nih.gov/pubmed/9502795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-07-02342.1998
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