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Synergistic Effects of Schwann- and Muscle-Derived Factors on Motoneuron Survival Involve GDNF and Cardiotrophin-1 (CT-1)

The survival of central neurons depends on multiple neurotrophic factors produced by different cell types. We demonstrate that media conditioned by muscle and Schwann cell lines show strong synergistic effects on survival of purified embryonic day 14.5 rat motoneurons in culture. Different lines of...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Arce, Vilma, Pollock, Richard A., Philippe, Jean-Marc, Pennica, Diane, Henderson, Christopher E., deLapeyrière, Odile
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792716/
https://ncbi.nlm.nih.gov/pubmed/9454853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-04-01440.1998
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