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Synergistic Effects of Schwann- and Muscle-Derived Factors on Motoneuron Survival Involve GDNF and Cardiotrophin-1 (CT-1)

The survival of central neurons depends on multiple neurotrophic factors produced by different cell types. We demonstrate that media conditioned by muscle and Schwann cell lines show strong synergistic effects on survival of purified embryonic day 14.5 rat motoneurons in culture. Different lines of...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Arce, Vilma, Pollock, Richard A., Philippe, Jean-Marc, Pennica, Diane, Henderson, Christopher E., deLapeyrière, Odile
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792716/
https://ncbi.nlm.nih.gov/pubmed/9454853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-04-01440.1998
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