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GFRα1 Is Required for Development of Distinct Subpopulations of Motoneuron

Glial cell-line derived neurotrophic factor (GDNF) and its relative neurturin (NTN) are potent trophic factors for motoneurons. They exert their biological effects by activating the RET tyrosine kinase in the presence of a glycosyl-phosphatidylinositol-linked co-receptor, either GFRα1 or GFRα2. By w...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Garcès, A., Haase, G., Airaksinen, M. S., Livet, J., Filippi, P., deLapeyrière, O.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772293/
https://ncbi.nlm.nih.gov/pubmed/10864957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-13-04992.2000
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