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GFRα1 Is Required for Development of Distinct Subpopulations of Motoneuron

Glial cell-line derived neurotrophic factor (GDNF) and its relative neurturin (NTN) are potent trophic factors for motoneurons. They exert their biological effects by activating the RET tyrosine kinase in the presence of a glycosyl-phosphatidylinositol-linked co-receptor, either GFRα1 or GFRα2. By w...

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Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Garcès, A., Haase, G., Airaksinen, M. S., Livet, J., Filippi, P., deLapeyrière, O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772293/
https://ncbi.nlm.nih.gov/pubmed/10864957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-13-04992.2000
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