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Inhibition of CPP32-Like Proteases Rescues Axotomized Retinal Ganglion Cells from Secondary Cell Death In Vivo

The majority of retinal ganglion cells (RGCs) degenerate and die after transection of the optic nerve (ON) in the adult rat. This secondary cell death can primarily be ascribed to apoptosis. Recent work strongly suggests a decisive role for a family of cysteine proteases, termed caspases, as mediato...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kermer, Pawel, Klöcker, Nikolaj, Labes, Monika, Bähr, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792678/
https://ncbi.nlm.nih.gov/pubmed/9614240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-12-04656.1998
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