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Inhibition of CPP32-Like Proteases Rescues Axotomized Retinal Ganglion Cells from Secondary Cell Death In Vivo

The majority of retinal ganglion cells (RGCs) degenerate and die after transection of the optic nerve (ON) in the adult rat. This secondary cell death can primarily be ascribed to apoptosis. Recent work strongly suggests a decisive role for a family of cysteine proteases, termed caspases, as mediato...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Kermer, Pawel, Klöcker, Nikolaj, Labes, Monika, Bähr, Mathias
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792678/
https://ncbi.nlm.nih.gov/pubmed/9614240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-12-04656.1998
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