Increased Synaptic Sprouting in Response to Estrogen via an Apolipoprotein E-Dependent Mechanism: Implications for Alzheimer’s Disease

Estrogen replacement therapy appears to delay the onset of Alzheimer’s disease (AD), but the mechanisms for this action are incompletely known. We show how the enhancement of synaptic sprouting by estradiol (E(2)) in response to an entorhinal cortex (EC) lesion model of AD may operate via an apolipo...

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Publicat a:J Neurosci
Autors principals: Stone, David J., Rozovsky, Irina, Morgan, Todd E., Anderson, Christopher P., Finch, Caleb E.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1998
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792662/
https://ncbi.nlm.nih.gov/pubmed/9547226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-09-03180.1998
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