Increased Synaptic Sprouting in Response to Estrogen via an Apolipoprotein E-Dependent Mechanism: Implications for Alzheimer’s Disease

Estrogen replacement therapy appears to delay the onset of Alzheimer’s disease (AD), but the mechanisms for this action are incompletely known. We show how the enhancement of synaptic sprouting by estradiol (E(2)) in response to an entorhinal cortex (EC) lesion model of AD may operate via an apolipo...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Stone, David J., Rozovsky, Irina, Morgan, Todd E., Anderson, Christopher P., Finch, Caleb E.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1998
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792662/
https://ncbi.nlm.nih.gov/pubmed/9547226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-09-03180.1998
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