Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction

Oxidative stress is implicated in neuronal apoptosis that occurs in physiological settings and in neurodegenerative disorders. Superoxide anion radical, produced during mitochondrial respiration, is involved in the generation of several potentially damaging reactive oxygen species including peroxyni...

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Vydáno v:J Neurosci
Hlavní autoři: Keller, Jeffrey N., Kindy, Mark S., Holtsberg, Fredrick W., St. Clair, Daret K., Yen, Hsiu-Chuan, Germeyer, Arriane, Steiner, Sheldon M., Bruce-Keller, Annadora J., Hutchins, James B., Mattson, Mark P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792529/
https://ncbi.nlm.nih.gov/pubmed/9425011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-02-00687.1998
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