Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction

Oxidative stress is implicated in neuronal apoptosis that occurs in physiological settings and in neurodegenerative disorders. Superoxide anion radical, produced during mitochondrial respiration, is involved in the generation of several potentially damaging reactive oxygen species including peroxyni...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Keller, Jeffrey N., Kindy, Mark S., Holtsberg, Fredrick W., St. Clair, Daret K., Yen, Hsiu-Chuan, Germeyer, Arriane, Steiner, Sheldon M., Bruce-Keller, Annadora J., Hutchins, James B., Mattson, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792529/
https://ncbi.nlm.nih.gov/pubmed/9425011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-02-00687.1998
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