Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library

BACKGROUND: Thyroid hormone receptors (TRs) are critical endocrine receptors that regulate a multitude of processes in adult and developing organisms, and thyroid hormone disruption is of high concern for neurodevelopmental and reproductive toxicities in particular. To date, only a small number of c...

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Detalhes bibliográficos
Publicado no:Environ Health Perspect
Main Authors: Paul-Friedman, Katie, Martin, Matt, Crofton, Kevin M., Hsu, Chia-Wen, Sakamuru, Srilatha, Zhao, Jinghua, Xia, Menghang, Huang, Ruili, Stavreva, Diana A., Soni, Vikas, Varticovski, Lyuba, Raziuddin, Razi, Hager, Gordon L., Houck, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado em: Environmental Health Perspectives 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792352/
https://ncbi.nlm.nih.gov/pubmed/31566444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP5314
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