Correction of Glycogen Synthase Kinase 3β in Myotonic Dystrophy 1 Reduces the Mutant RNA and Improves Postnatal Survival of DMSXL Mice

Myotonic dystrophy type 1 (DM1) is a multisystem neuromuscular disease without cure. One of the possible therapeutic approaches for DM1 is correction of the RNA-binding proteins CUGBP1 and MBNL1, misregulated in DM1. CUGBP1 activity is controlled by glycogen synthase kinase 3β (GSK3β), which is elev...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Wang, Mei, Weng, Wen-Chin, Stock, Lauren, Lindquist, Diana, Martinez, Ana, Gourdon, Genevieve, Timchenko, Nikolai, Snape, Mike, Timchenko, Lubov
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791656/
https://ncbi.nlm.nih.gov/pubmed/31383751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00155-19
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak