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Tasquinimod targets suppressive myeloid cells in the tumor microenvironment

Infiltrating myeloid derived suppressor cells and tumor-associated macrophages (TAMs) are important components of the immunosuppressive tumor microenvironment. We recently reported that tasquinimod, which binds to S100A9, impairs both infiltration and function of these cells. Here we discuss the und...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncoimmunology
Main Authors: Shen, Li, Pili, Roberto
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791429/
https://ncbi.nlm.nih.gov/pubmed/31646064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1072672
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