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Tasquinimod targets suppressive myeloid cells in the tumor microenvironment

Infiltrating myeloid derived suppressor cells and tumor-associated macrophages (TAMs) are important components of the immunosuppressive tumor microenvironment. We recently reported that tasquinimod, which binds to S100A9, impairs both infiltration and function of these cells. Here we discuss the und...

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Détails bibliographiques
Publié dans:Oncoimmunology
Auteurs principaux: Shen, Li, Pili, Roberto
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791429/
https://ncbi.nlm.nih.gov/pubmed/31646064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1072672
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