Vascular Endothelial Growth Factor Is Regulated by the Canonical and Noncanonical Transforming Growth Factor-β Pathway in Synovial Fibroblasts Derived from Osteoarthritis Patients

BACKGROUND: Previous studies suggest the presence of an association of vascular endothelial growth factor (VEGF) with osteoarthritis (OA) severity and pain in patients with knee OA. VEGF expression in human synovial fibroblasts (SFs) is induced by transforming growth factor-beta (TGFβ). However, the...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Takano, Shotaro, Uchida, Kentaro, Shoji, Shintaro, Itakura, Makoto, Iwase, Dai, Aikawa, Jun, Mukai, Manabu, Sekiguchi, Hiroyuki, Inoue, Gen, Takaso, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791277/
https://ncbi.nlm.nih.gov/pubmed/31662989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6959056
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